Friday Night Stand-up with Greg Giraldo was a programing block hosted by Greg Giraldo. It aired on Comedy Central from 8-11 PM on Friday nights. It premiered in 2005. Giraldo interviewed guests in front of a live audience while introducing comedy specials. Some comedians who have appeared include Jeff Dunham, Carlos Mencia and Dane Cook. In 2006, the title was changed to Stand-Up Nation with Greg Giraldo.